First-in-Class Star-Shaped Triazine Dendrimers Endowed with MMP-9 Inhibition and VEGF Suppression Capacity: Design, Synthesis, and Anticancer Evaluation

Autor:	Nesreen S. Haiba, Hosam H. Khalil, Ahmed Bergas, Marwa M. Abu-Serie, Sherine N. Khattab, Mohamed Teleb
Rok vydání:	2022
Předmět:	General Chemical Engineering General Chemistry
Zdroj:	ACS Omega. 7:21131-21144
ISSN:	2470-1343
DOI:	10.1021/acsomega.2c01949
Popis:	Off-target side effects are major challenges hindering the clinical success of matrix metalloproteinase (MMP) inhibitors. Various targeting strategies revitalized MMP research to eliminate this drawback. Herein, we developed
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f2b1a01769481507eec6acb48f7bb6 https://doi.org/10.1021/acsomega.2c01949 Zobrazit plný text záznamu