Thyroid Acropachy: A Rare Manifestation of Graves Disease in Joints
| Autor: | João H. Romaldini, Danilo Villagelin, Roberto B. Santos, Nicolas Perini |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
endocrine system genetic structures endocrine system diseases business.industry Graves' disease Thyroid 030209 endocrinology & metabolism Case Reports General Medicine Acropachy medicine.disease RC648-665 Dermatology eye diseases Diseases of the endocrine glands. Clinical endocrinology 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure SKIN TIGHTNESS 030220 oncology & carcinogenesis medicine business |
| Zdroj: | AACE Clinical Case Reports, Vol 5, Iss 6, Pp e369-e371 (2019) |
| ISSN: | 2376-0605 |
| Popis: | Objective: The objective of this report was to describe a patient with Graves acropachy, a rare manifestation of Graves disease (GD) that is clinically defined by skin tightness, digital clubbing, small-joint pain, and soft tissue edema progressing over months or years with gradual curving and enlargement of the fingers. Methods: The patient was evaluated regarding thyroid function (serum free T4 [FT4] and thyroid-stimulating hormone [TSH] quantifications) and autoimmunity biomarkers (thyroid receptor antibody [TRAb]) as well as radiographic investigation of the extremities. Results: A 52-year-old man presented with a history of thyrotoxicosis and clinical signs of Graves orbitopathy. Laboratory tests showed suppressed TSH (0.01 UI/L; normal, 0.4 to 4.5 UI/L) and elevated serum FT4 (7.77 ng/dL; normal, 0.93 to 1.7 ng/dL), with high TRAb levels (40 UI/L; normal |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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