The impact of the IL-11:IL-17 ratio on the chronic periodontitis pathogenesis: a preliminary report
| Autor: | Ezel Berker, Fatma Yeşim Bozkurt, Ersin Uskun, Z. Yetkin Ay, Recep Sutcu |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Gastroenterology Crevicular fluid Pathogenesis Immune system Preliminary report Bleeding time Internal medicine Periodontal Attachment Loss Humans Periodontal Pocket Medicine General Dentistry Aged medicine.diagnostic_test business.industry Dental Plaque Index Interleukin-17 Interleukin Gingival Crevicular Fluid Middle Aged Interleukin-11 medicine.disease Chronic periodontitis Otorhinolaryngology Chronic Periodontitis Female Interleukin 17 Periodontal Index Gingival Hemorrhage business |
| Zdroj: | Oral Diseases. 15:93-99 |
| ISSN: | 1601-0825 1354-523X |
| DOI: | 10.1111/j.1601-0825.2008.01497.x |
| Popis: | Objective: An imbalance in the pro- and anti-inflammatory cytokines may be responsible for periodontal breakdown through immune responses. This study aimed to determine the total amount, concentration and ratio of interleukin (IL)-11 and IL-17 in gingival crevicular fluid (GCF) of chronic periodontitis (CP) patients. Materials and methods: Forty CP patients and 20 healthy controls (C) were included. The CP group was divided into two subgroups in line with the probing depth (PD) in GCF-sampling sites (CPa: PD ≥ 5 mm, CPb: PD ≤ 4 mm). For each patient, gingival index, plaque index, gingival bleeding time index, PD, and clinical attachment level values were recorded. IL-11 and IL-17 in GCF were evaluated by enzyme-linked immunosorbent assays. Results: The total amount and concentration of IL-11 and IL-17 were significantly lower in the CPa group (P |
| Databáze: | OpenAIRE |
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