Impact of parental cancer on IQ, stress resilience, and physical fitness in young men
| Autor: | Fang Fang, Katja Fall, Unnur Valdimarsdóttir, Kamila Czene, Ruoqing Chen, Beatrice Kennedy |
|---|---|
| Přispěvatelé: | Miðstöð í lýðheilsuvísindum (HÍ), The Centre of Public Health Sciences (UI), Heilbrigðisvísindasvið (HÍ), School of Health Sciences (UI), Háskóli Íslands, University of Iceland |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Heilsufar
Epidemiology media_common.quotation_subject Intelligence Physical fitness Börn 030204 cardiovascular system & hematology Parental Death 03 medical and health sciences 0302 clinical medicine Child of impaired parents medicine cancer Clinical Epidemiology Stress resilience 030212 general & internal medicine Greind resilience Cancer Krabbamein media_common Multinomial logistic regression Original Research Resilience Krabbameinssjúklingar business.industry Seigla (persónuleikasálfræði) intelligence medicine.disease Confidence interval Relative risk physical fitness Psychological resilience business child of impaired parents Demography |
| Zdroj: | Clinical Epidemiology |
| ISSN: | 1179-1349 |
| Popis: | Background: A parental cancer diagnosis is a stressful life event, potentially leading to increased risks of mental and physical problems among children. This study aimed to investigate the associations of parental cancer with IQ, stress resilience, and physical fitness of the affected men during early adulthood. Materials and methods: In this Swedish population-based study, we included 465,249 men born during 1973–1983 who underwent the military conscription examination around the age of 18 years. We identified cancer diagnoses among the parents of these men from the Cancer Register. IQ, stress resilience, and physical fitness of the men were assessed at the time of conscription and categorized into three levels: low, moderate, and high (reference category). We used multinomial logistic regression to assess the studied associations. Results: Overall, parental cancer was associated with higher risks of low stress resilience (relative risk ratio [RRR]: 1.09 [95% confidence interval (CI) 1.04–1.15]) and low physical fitness (RRR: 1.12 [95% CI 1.05–1.19]). Stronger associations were observed for parental cancer with a poor expected prognosis (low stress resilience: RRR: 1.59 [95% CI 1.31–1.94]; low physical fitness: RRR: 1.45 [95% CI 1.14–1.85]) and for parental death after cancer diagnosis (low stress resilience: RRR: 1.29 [95% CI 1.16–1.43]; low physical fitness: RRR: 1.40 [95% CI 1.23–1.59]). Although there was no overall association between parental cancer and IQ, parental death after cancer diagnosis was associated with a higher risk of low IQ (RRR: 1.11 [95% CI 1.01–1.24]). Conclusion: Parental cancer, particularly severe and fatal type, is associated with higher risks of low stress resilience and low physical fitness among men during early adulthood. Men who experienced parental death after cancer diagnosis also have a higher risk of low IQ. This study was supported by the Swedish Research Council for Health, Working Life and Welfare (grant number: 2012- 0498), and the Swedish Cancer Society (grant number: CAN 2014/417). Dr Fang was supported by the Karolinska Institutet (Senior Researcher Award and the Strategic Research Program in Epidemiology). Dr Chen was supported by the China Scholarship Council (no. 201206100002). |
| Databáze: | OpenAIRE |
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