Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs

Autor:	Jorge A. R. Salvador, Yongkui Jing, Vânia M. Moreira, Bruno M. F. Gonçalves, Ana S. Leal
Rok vydání:	2012
Předmět:	Biological Products Triterpenoid Molecular Structure Organic Chemistry Drug Discovery Humans Pentacyclic triterpenoids Antineoplastic Agents Biology Drug Screening Assays Antitumor Pentacyclic Triterpenes Biochemistry Combinatorial chemistry
Zdroj:	Natural product reports. 29(12)
ISSN:	1460-4752
Popis:	Covering: up to December 2011 This review highlights the potential of natural and semisynthetic ursane-type triterpenoids as candidates for the design of multi-target bioactive compounds, with focus on their anticancer effects. A brief illustration of the biosynthesis, sources, and general biological effects of the main classes of naturally occurring pentacyclic triterpenoids (PTs) are provided.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d4a2c7a1a12326f695a4009f675503 https://pubmed.ncbi.nlm.nih.gov/23047641 Zobrazit plný text záznamu