Effect of Direct Stimulation of the Cochleovestibular Nerve on Tinnitus: A Long-Term Follow-Up Study
| Autor: | Janke Stienstra, J. Marc C. van Dijk, Bernard F. A. M. van der Laan, Rolien Free, Pim van Dijk, Minke J C van den Berge |
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| Přispěvatelé: | Perceptual and Cognitive Neuroscience (PCN), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Man, Biomaterials and Microbes (MBM), Movement Disorder (MD) |
| Rok vydání: | 2016 |
| Předmět: |
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medicine.medical_specialty Visual analogue scale Hearing loss medicine.medical_treatment COCHLEAR IMPLANT SPINAL-CORD STIMULATION Vestibulocochlear nerve Electric Stimulation Therapy Vestibular Nerve Prosthesis Design 03 medical and health sciences Tinnitus 0302 clinical medicine NEUROSTIMULATION Vertigo Cochlear implant otorhinolaryngologic diseases Medicine Humans 030223 otorhinolaryngology Neurostimulation Cochlear Nerve SUPPRESSION Aged HEARING biology medicine.diagnostic_test business.industry Middle Aged biology.organism_classification Surgery Implantable Neurostimulators Treatment Outcome Anesthesia Female Neurology (clinical) Pure tone audiometry medicine.symptom business 030217 neurology & neurosurgery CHRONIC PAIN Follow-Up Studies |
| Zdroj: | World neurosurgery, 98, 571-577. ELSEVIER SCIENCE INC |
| ISSN: | 1878-8769 1878-8750 |
| Popis: | OBJECTIVE: Tinnitus is a common entity that may lead to severe impairment in quality of life. An adequate treatment modality for severe tinnitus is currently lacking. Neurostimulation of the auditory tract may serve as a promising adjunct in tinnitus treatment. The aim is to investigate the effect of direct stimulation on the cochleovestibular nerve for intractable tinnitus.METHODS: This study was conducted at the University Medical Center Groningen, The Netherlands. We studied 10 patients with severe, unilateral, intractable tinnitus, who were implanted with a cuff electrode around the cochleovestibular nerve between 2001 and 2013. All patients had preoperative ipsilateral hearing loss. Tinnitus Handicap Inventory (THI) scores and audiometric values were collected. Treatment success was determined based on the self-assessment of satisfactory usage by each patient.RESULTS: The mean preoperative tinnitus duration was 8.0 +/- 5.9 years. The preoperative THI score was 71 +/- 18 points. During mean follow-up of 49 months, the mean THI reduction was 24 +/- 26 points (P = 0.02). Treatment was regarded successful in 6 patients (60%). In these patients, tinnitus did not disappear, but transformed into a more bearable sound. In 4 patients, transient complications occurred, and 1 patient experienced permanent vertigo postoperatively. Furthermore, hearing deterioration was a result of implantation in 86% of the patients.CONCLUSIONS: Direct neurostimulation resulted in treatment success in a small majority of the patients, with a significant decrease in THI score. However, because of a high risk of additional hearing damage, this technique seems not viable for patients with moderate hearing loss. |
| Databáze: | OpenAIRE |
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