Does reflux have an effect on nasal mucociliary transport?
| Autor: | Sema Zer Toros, Baris Naiboglu, Arman Tek, Talip Murat Eriman, Ruhi Durmus, Züleyha Akkan Çetinkaya, Mesut Sezikli, Erol Egeli |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Mucous membrane of nose Gastroenterology Laryngopharyngeal reflux Young Adult Internal medicine medicine Laryngopharyngeal Reflux Humans Prospective Studies Prospective cohort study Nose Aged Esophageal disease business.industry Reflux General Medicine Middle Aged medicine.disease digestive system diseases Nasal Mucosa medicine.anatomical_structure Otorhinolaryngology Mucociliary Clearance Case-Control Studies Referral center Female business After treatment |
| Zdroj: | Acta oto-laryngologica. 130(9) |
| ISSN: | 1651-2251 |
| Popis: | Gastroesophageal and laryngopharyngeal reflux were found to have no effect on nasal mucociliary transport.Gastroesophageal and laryngopharyngeal reflux have been recognized as causative factors for chronic rhinosinusitis but no definite mechanism has been described yet. We aimed to determine whether gastroesophageal and laryngopharyngeal reflux impair nasal mucociliary transport.This was a prospective cohort study in a tertiary referral center. Fifty patients with both laryngopharyngeal and gastroesophageal reflux comprised the study group. Reflux syndrome index and reflux finding score were calculated for each patient before and after treatment. Antireflux medication was given for 12 weeks. The control group consisted of 30 healthy volunteers. Nasal mucociliary transport was assessed by means of the saccharine test. It was performed before and after the treatment. Statistical analysis was performed using the saccharine test results of the study and control groups.No statistical difference was found between the saccharine test results of the study group and control group before treatment. The differences between the pretreatment and post-treatment reflux symptom index and reflux finding scores were statistically significant. The difference between the post-treatment saccharine test results of the patients in whom reflux scores returned to normal and those with remaining high scores was not statistically significant. |
| Databáze: | OpenAIRE |
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