A Systematic Review Supporting the Endocrine Society Guidelines: Management of Diabetes and High Risk of Hypoglycemia

Autor: Victor D Torres Roldan, Meritxell Urtecho, Tarek Nayfeh, Mohammed Firwana, Kalpana Muthusamy, Bashar Hasan, Rami Abd-Rabu, Andrea Maraboto, Amjad Qoubaitary, Larry Prokop, David C Lieb, Anthony L McCall, Zhen Wang, Mohammad Hassan Murad
Rok vydání: 2022
Předmět:
Zdroj: The Journal of clinical endocrinology and metabolism.
ISSN: 1945-7197
Popis: Context Interventions targeting hypoglycemia in people with diabetes are important for improving quality of life and reducing morbidity and mortality. Objective To support development of the Endocrine Society Clinical Practice Guideline for management of individuals with diabetes at high risk for hypoglycemia. Methods We searched several databases for studies addressing 10 questions provided by a guideline panel from the Endocrine Society. Meta-analysis was conducted when feasible. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology was used to assess certainty of evidence. Results We included 149 studies reporting on 43 344 patients. Continuous glucose monitoring (CGM) reduced episodes of severe hypoglycemia in patients with type 1 diabetes (T1D) and reduced the proportion of patients with hypoglycemia (blood glucose [BG] levels Conclusion This systematic review summarized the best available evidence about several interventions addressing hypoglycemia in people with diabetes. This evidence base will facilitate development of clinical practice guidelines by the Endocrine Society.
Databáze: OpenAIRE