Reducing the Amount of Monomers in Intraocular Lenses through Sterilization by Gamma Radiation
| Autor: | Klaus Ludwig, O. F. Scheiffarth, L. von Meyer |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Chromatography
Gas Polymethyl methacrylate medicine.medical_treatment Color Intraocular lens Methylmethacrylate Radiation Cellular and Molecular Neuroscience chemistry.chemical_compound Optics Radiation Ionizing medicine Methylmethacrylates Methyl methacrylate Lenses Intraocular Ethylene oxide business.industry Osmolar Concentration Radiochemistry Sterilization General Medicine Sterilization (microbiology) Sensory Systems Ophthalmology Monomer chemistry Intraocular lenses Gamma Rays business |
| Zdroj: | Ophthalmic Research. 20:304-307 |
| ISSN: | 1423-0259 0030-3747 |
| DOI: | 10.1159/000266732 |
| Popis: | Sterile inflammatory reactions of varying degrees are a rare, but not uncommon, complication after intraocular lens implantation. At present we still do not know the cause of these processes, but we consider two chemical substances contained in the lens at least as risk factors for them: monomeric methyl methacrylate, which is present in any lens made from polymethyl methacrylate (Perspex), and ethylene oxide, an extremely toxic agent, which is absorbed by the lens during sterilization with this gas. Gas chromatographic investigations show that under sterilization of intraocular lenses by 60Co radiation the amount of monomeric methyl methacrylate in the lens can be reduced drastically. Also, any contamination of the lens by ethylene oxide is avoided. Therefore, at least two important arguments speak in favor of this alternative sterilization technique. |
| Databáze: | OpenAIRE |
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