Chemoselective synthesis of thieno[3,2-c][1,8]naphthyridin-4(5H)-ones by tandem cyclization

Autor:	Rafique‐ul‐Islam Rafique‐ul‐Islam, Majumdar Krishna C. Majumdar Krishna C.
Rok vydání:	2007
Předmět:	chemistry.chemical_compound Tandem Chemistry Intramolecular force Yield (chemistry) Heteroatom Michael reaction Organic chemistry Sulfoxide General Medicine General Chemistry Sigmatropic reaction Medicinal chemistry
Zdroj:	Heteroatom Chemistry. 18:87-92
ISSN:	1098-1071 1042-7163
DOI:	10.1002/hc.20234
Popis:	A number of the thieno[3,2-c][1,8]-naphthyridin-4(5H)-ones are chemoselectively synthesized from 4-(4′-aryloxybut-2′-ynylthio)-1-phenyl-1,8-naphthyridin-2(1H)-ones in 82–90% yield by the formation of sulfoxide, followed by [2,3] and [3,3]sigmatropic rearrangement and an intramolecular Michael addition. © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:87–92, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20234
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a8c1eb5a6264768bb10258ec69dcc0 https://doi.org/10.1002/hc.20234 Zobrazit plný text záznamu