Naturally acquired antibodies to tetanus toxin in humans and animals from the galápagos islands
| Autor: | Focaccia R, M T C Focaccia, C. C. Mazza, R Veronesi, M. N. Honningman, F. Carraro, A. L. Coscina, B. Bizzini |
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| Rok vydání: | 1983 |
| Předmět: |
Adult
Adolescent Enzyme-Linked Immunosorbent Assay medicine.disease_cause complex mixtures Serology Dogs Tetanus Toxin medicine Tetanus Toxoid Immunology and Allergy Animals Humans Horses Child Perissodactyla Aged biology Tetanus Toxin business.industry Indians South American Mean age Middle Aged medicine.disease Virology Antibodies Bacterial Vaccination Titer Infectious Diseases Immunization Animals Domestic Child Preschool Immunology biology.protein Cattle Ecuador Antibody business Brazil |
| Zdroj: | The Journal of infectious diseases. 147(2) |
| ISSN: | 0022-1899 |
| Popis: | A serologic survey using a highly sensitive enzyme-linked immunosorbent assay confirmed the anticipated finding of naturally acquired antibodies to tetanus toxin both in humans and animals on the Galapagos Islands. In 57 inhabitants (mean age, 31.3 years) who had not been vaccinated against tetanus, antibody to tetanus toxin was detected in the blood in varying titers (geometric mean [reciprocal] titer [GMT], 0.015 international units [IU]/ml). In one individual the titer of antibody was greater than 12.5 IU/ml. Two individuals who had never been vaccinated against tetanus but who had reported having had clinical tetanus had titers of antibody to tetanus toxin of 0.02 IU/ml and 0.3 IU/ml, respectively. All nine of the animals studied showed antibody to tetanus toxin (GMT, 0.028 IU/ml). |
| Databáze: | OpenAIRE |
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