Effects of humic acids, para-aminobenzoic acid and ascorbic acid on the N-nitrosation of the carbamate insecticide propoxur and on the mutagenicity of nitrosopropoxur
| Autor: | S.A. Badaev, F. Pospíšil, T. Gichner, J. Velemínský |
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| Rok vydání: | 1990 |
| Předmět: |
endocrine system
Nitroso Compounds Nitrosation Health Toxicology and Mutagenesis Mutagen Ascorbic Acid Propoxur medicine.disease_cause chemistry.chemical_compound Genetics medicine Sodium nitrite Molecular Biology Humic Substances Chromatography Mutagenicity Tests fungi food and beverages Plants Pesticide Ascorbic acid Biochemistry chemistry 4-Aminobenzoic Acid Antimutagen Mutagens |
| Zdroj: | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 229:37-41 |
| ISSN: | 0027-5107 |
| Popis: | Nitrosation of the carbamate insecticide propoxur at pH 3 and 37°C was determined colorimetrically and found to be time- and sodium nitrite concentration-dependent. Nitrosated propoxur was mutagenic when exposed to the seeds of the higher plant Arabidopsis thaliana but the formation of nitrosopropoxur, the presumed mutagen, was inhibited by humic acids, para-aminobenzoic acid and ascorbic acid. These agents also reduced the mutagenicity of performed nitrosopropoxur. |
| Databáze: | OpenAIRE |
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