Nonalcoholic fatty liver disease‐related cirrhosis is commonly unrecognized and associated with hepatocellular carcinoma
| Autor: | Luis Calzadilla Bertot, Helena Lan-In Ching, George Garas, Gary P. Jeffrey, Michael C. Wallace, Leon A. Adams, Gerry MacQuillan |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Cirrhosis Hepatology business.industry Original Articles medicine.disease Gastroenterology digestive system diseases 03 medical and health sciences Liver disease 030104 developmental biology 0302 clinical medicine Fibrosis Internal medicine Concomitant Hepatocellular carcinoma Nonalcoholic fatty liver disease medicine Original Article 030211 gastroenterology & hepatology business Varices |
| Zdroj: | Hepatology Communications |
| ISSN: | 2471-254X |
| Popis: | Determination of cirrhosis in nonalcoholic fatty liver disease (NAFLD) is important as it alters prognosis and management. We aimed to examine whether cirrhosis was diagnosed incidentally or intentionally in patients with NAFLD. We reviewed 100 patients with NAFLD cirrhosis to determine mode of cirrhosis diagnosis (incidental or by intent), severity of liver disease at diagnosis, diagnostician, and previous clinical imaging or laboratory evidence of unrecognized cirrhosis. The majority (66/100) of patients with NAFLD cirrhosis were diagnosed incidentally, with the majority of these (74%) diagnosed with NAFLD simultaneously. Those with incidental cirrhosis diagnoses had more deranged platelet and international normalized ratio levels (P |
| Databáze: | OpenAIRE |
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