How does clinical profile and outcome differ in patients with Chronic Kidney Disease undergoing percutaneous coronary revascularization according to the severity of CKD? – CHANNEL Study
| Autor: | Panwar Jasraj, Jain Sharad, Meniya Jayesh, Sharma Kamal, Bhatia Sanjeev, Charaniya Riyaz, Patel Iva, Patel Krutika, Jhameria Jevin |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
RD1-811 medicine.medical_treatment Renal function MACE Coronary artery disease Percutaneous Coronary Intervention Risk Factors Internal medicine Chronic kidney disease medicine Humans Diseases of the circulatory (Cardiovascular) system Prospective Studies Risk factor Renal Insufficiency Chronic Percutaneous coronary angioplasty business.industry Percutaneous coronary intervention medicine.disease ACS Treatment Outcome RC666-701 Cohort Conventional PCI Cardiology Original Article Surgery Cardiology and Cardiovascular Medicine business Mace Kidney disease Glomerular Filtration Rate |
| Zdroj: | Indian Heart Journal, Vol 73, Iss 4, Pp 476-480 (2021) Indian Heart Journal |
| ISSN: | 0019-4832 |
| Popis: | Background: Chronic kidney disease (CKD) is an independent risk factor for the development of coronary artery disease. We evaluated outcomes amongst patients of CKD undergoing percutaneous coronary intervention (PCI) as assessed on severity of CKD based on estimated glomerular filtration rate (eGFR) at the time of PCI. Method and materials: We analyzed 100 consecutive CKD patients who underwent PCI and were followed up for 1 year; an observational, prospective, open-label study. Multivariate and Receiver operator characteristics (ROC) analysis was used to determine the cut point ofeGFR for predicting 4-P major adverse cardiac events (MACE) outcomes defined as the composite of Cardiovascular (CV) mortality, heart failure hospitalization (HHF), repeat revascularization and non-fatal MI over 1 year follow up. Results: According to eGFR cut-off value derived from ROC, patients were divided in to two groups based on eGFR cut-off of 36.25 mL/min/1.73 m2. Majority of patients (79%) were in Group 1 (eGFR >36.25 mL/min/1.73 m2). Group 2 had Lower HbA1C, hemoglobin and elevated level of urea as compared to group:1 (p=0.002 |
| Databáze: | OpenAIRE |
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