Nanoparticles for drug delivery: The need for precision in reporting particle size parameters
| Autor: | Marie Gaumet, Robert Gurny, Florence Delie, Angelica Vargas |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Biodistribution
Materials science Drug Industry Polymers Surface Properties Chemistry Pharmaceutical Pharmaceutical Science Nanoparticle Nanotechnology Drug Delivery Systems Animals Humans Technology Pharmaceutical Small particles Particle Size Microparticle Drug Carriers ddc:615 General Medicine Nanostructures Nanomedicine Solubility Drug delivery Nanoparticles Particle size Drug carrier Biotechnology |
| Zdroj: | European Journal of Pharmaceutics and Biopharmaceutics, Vol. 69 (2008) pp. 1-9 |
| ISSN: | 0939-6411 |
| DOI: | 10.1016/j.ejpb.2007.08.001 |
| Popis: | Polymeric drug-loaded nanoparticles have been extensively studied in the field of drug delivery. Biodistribution depends on the physicochemical properties of particles, especially size. The global message from the literature is that small particles have an enhanced ability to reach their target. The present review highlights the difficulties in validating the data from biodistribution studies without accurate particle size determination. |
| Databáze: | OpenAIRE |
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