Infection surveillance in pediatric hematopoietic stem cell transplantation recipients
| Autor: | Roberta Maia de Castro Romanelli, Wanessa Trindade Clemente, Antonio Vaz de Macedo, Paulo Henrique Orlandi Mourão, Karla Emília de Sá Rodrigues, Fabiana Maria Kakehashi, Daniela Caldas Teixeira, Helena Duani, Lilian Martins Oliveira Diniz |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Adolescent medicine.medical_treatment Hematopoietic stem cell transplantation Infections 03 medical and health sciences 0302 clinical medicine medicine Humans 030212 general & internal medicine Aplastic anemia Intensive care medicine Child Infection surveillance Retrospective Studies Cross Infection business.industry Incidence (epidemiology) Incidence Ethics committee Age Factors Hematopoietic Stem Cell Transplantation Infant Retrospective cohort study Hematology General Medicine medicine.disease Transplant Recipients Transplantation Leukemia 030220 oncology & carcinogenesis Child Preschool Health Care Surveys Female business Brazil |
| Zdroj: | European journal of haematology. 100(1) |
| ISSN: | 1600-0609 |
| Popis: | Objective Describe the profile of reported Healthcare-Associated Infections (HAIs) in pediatric patients submitted to hematopoietic stem cell transplantation (HSCT) at a reference center. Methods Retrospective cohort of pediatric patients who were submitted to HSCT from 2008 to 2016. The criteria for HAI were based on those established by the National Healthcare Safety Network. Data were collected by active surveillance performed daily by professionals. This study was approved by the Institutional Research Ethics Committee. Results A total of 86 HSCTs were performed in 81 patients younger than 18 years of age (median, 10 years). Of these, 69 (85%) were males. Aplastic anemia and leukemia were the main diagnoses. A total of 140 HAIs were diagnosed with an incidence density of 28.2 infections/1.000 patient-days. The most common HAI was Laboratory Confirmed Bloodstream Infection (46), the majority of which was reported to be central venous catheter-associated (43). Gram-negative bacteria were the most prevalent microorganisms (58.5%). Almost all the infections occurred until 30 days after transplantation, and 17 deaths were observed within 180 days after the procedure. Conclusion Active surveillance of HAIs in HSCT children allowed the evaluation of the incidence and profile of HAIs, which is essential for the healthcare of these patients. This article is protected by copyright. All rights reserved. |
| Databáze: | OpenAIRE |
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