Role of Therapeutic Plasma Exchange in Treatment of Tumefactive Multiple Sclerosis-Associated Low CD4 and CD8 Levels
| Autor: | Charles Kososky, Sahana Ramanujam, Bahareh Hassanzadeh, Leema Reddy Peddareddygari, Raji P. Grewal, Robert Moser, Kristen Lew, John E. Donahue, Nishith Mewada |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty Lymphocyte Central nervous system Case Report lcsh:RC346-429 03 medical and health sciences 0302 clinical medicine Tumefactive multiple sclerosis Lymphopenia medicine Plasma exchange lcsh:Neurology. Diseases of the nervous system Intravenous methylprednisolone business.industry medicine.disease Inflammatory demyelinating disease 030104 developmental biology medicine.anatomical_structure Immunology Therapeutic plasma exchange Neurology (clinical) business 030217 neurology & neurosurgery CD8 |
| Zdroj: | Case Reports in Neurology, Vol 8, Iss 2, Pp 179-184 (2016) Case Reports in Neurology |
| Popis: | We report a 35-year-old healthy male who developed central nervous system inflammatory demyelinating disease consistent with tumefactive multiple sclerosis. About 2 weeks after onset of symptoms and prior to initiation of therapy, the patient had lymphopenia and low CD4 and CD8 levels. His lymphocyte count was 400 cells/µl (850–3,900 cells/µl), CD4 was 193 cells/µl (490–1,740 cells/µl) and CD8 was 103 cells/µl (180–1,170 cells/µl). He was treated with intravenous methylprednisolone followed by therapeutic plasma exchange, the levels of CD4 and CD8 normalized, and ultimately, he recovered completely. |
| Databáze: | OpenAIRE |
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