Antibacterial and antifungal activities of some trimethoprim salts

Autor: Fatih Demirci, Gökalp İşcan, Hülya Karaca, Kadriye Benkli, Yağmur Tunalı
Přispěvatelé: Anadolu Üniversitesi, Eczacılık Fakültesi, Mikrobiyoloji Anabilim Dalı, Tunalı, Yağmur, İşcan, Gökalp, Demirci, Fatih, Benkli, Kadriye
Rok vydání: 2011
Předmět:
Zdroj: Medicinal Chemistry Research. 21:932-935
ISSN: 1554-8120
1054-2523
DOI: 10.1007/s00044-011-9605-5
Popis: WOS: 000303471900027
In this study, the antimicrobial activities of Trimethoprim (1), Trimethoprim + Maleic acid (2), Trimethoprim + Oxalic acid dihydrate (3), and Trimethoprim + trans-1,2-Cyclohexanedicarboxylic acid (4) were investigated for their in vitro growth inhibitory activity against human pathogenic as some bacteria and fungi. Substances were tested using the micro-broth dilution assay. The chemical agents showed the same activity against Escherichia coli, Pseudomonas aeruginosa, and Proteus vulgaris. Inhibitory activities of test chemicals against different Candida strains were determined to be widely moderate.
Anadolu University, Commission of Scientific Research Projects
Authors are grateful to Anadolu University, Commission of Scientific Research Projects for support of this study.
Databáze: OpenAIRE