Zika Virus Infection: Current Concerns and Perspectives
| Autor: | Eileen YinYien Lau, Wei Lim Foo, Xi Jin Theam, Yen Ling Lok, Mari Kannan Maharajan, Jian Feng Chu, Heuy Mien Ye, Aruna Ranjan, Zhi Xin Chai |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Microcephaly Aedes aegypti Antiviral Agents Dengue fever Zika virus Dengue Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Risk Factors Immunology and Allergy Medicine Animals Humans 030212 general & internal medicine Mortality Intensive care medicine biology business.industry Transmission (medicine) Zika Virus Infection Viral Vaccine Public health Research Outbreak Disease Management Viral Vaccines General Medicine Zika Virus biology.organism_classification medicine.disease Virology Viral Tropism 030104 developmental biology Chikungunya Fever Cytokines business |
| Zdroj: | Clinical reviews in allergyimmunology. 51(3) |
| ISSN: | 1559-0267 |
| Popis: | The Zika virus outbreaks highlight the growing importance need for a reliable, specific and rapid diagnostic device to detect Zika virus, as it is often recognized as a mild disease without being identified. Many Zika virus infection cases have been misdiagnosed or underreported because of the non-specific clinical presentation. The aim of this review was to provide a critical and comprehensive overview of the published peer‐reviewed evidence related to clinical presentations, various diagnostic methods and modes of transmission of Zika virus infection, as well as potential therapeutic targets to combat microcephaly. Zika virus is mainly transmitted through bites from Aedes aegypti mosquito. It can also be transmitted through blood, perinatally and sexually. Pregnant women are advised to postpone or avoid travelling to areas where active Zika virus transmission is reported, as this infection is directly linked to foetal microcephaly. Due to the high prevalence of Guillain-Barre syndrome and microcephaly in the endemic area, it is vital to confirm the diagnosis of Zika virus. Zika virus infection had been declared as a public health emergency and of international concern by the World Health Organisation. Governments and agencies should play an important role in terms of investing time and resources to fundamentally understand this infection so that a vaccine can be developed besides raising awareness. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink