Asthma, lung function and sensitization in school children with a history of bronchiolitis

Autor: Sofia Ktenidou-Kartali, Victor Aivazis, Athanasios Chatzimichael, Dimitrios Cassimos, Gregorios Tripsianis, Michael Anthracopoulos, Stefanos Gardikis, Aggelos Tsalkidis, Anastasia Stogiannidou
Rok vydání: 2008
Předmět:
Zdroj: Pediatrics International. 50:51-56
ISSN: 1442-200X
1328-8067
DOI: 10.1111/j.1442-200x.2007.02509.x
Popis: Background: The purpose of the present retrospective study was to investigate the association of school-age asthma with acute-bronchiolitis and examine the influence of potential risk factors. Methods: One hundred and eighty-nine children aged 7.5 ± 2.2 years consecutively hospitalized for respiratory syncytial virus (RSV)-positive acute bronchiolitis during infancy were evaluated by clinical examination and measurement of peak expiratory flow (PEFR), spirometry, IgE and skin-prick testing. Their pulmonary function was compared with that of 60 non-asthmatic matched controls. Results: Of the entire cohort 57.1% were diagnosed as asthmatic. PEFR, the 1-second forced expiratory volume and forced expiratory flow of 50% vital capacity of children with a history of acute bronchiolitis were statistically significantly lower than in the control group (all P
Databáze: OpenAIRE