Exploring the predictive value of specific symptom as prognostic factor: Assessment of group-confined likelihood ratio for symptom ‘Headache’ in 20 lesser-known drugs
| Autor: | Sunil Ramteke, J. P. Singh, Siva Prasad Goli, Pramodji Singh, Abhijit Chakma, Raj K Manchanda, Manas Ranjan Sarangi, Partha Sarathi Chakraborty, O. P. Singh, Mahesh Kumar Sah, Amulya Ratan Sahoo, Pushpa Devi, Pankaj Kumar Pradhan, KK Avinash, Suhana Panaparambil Azis, Abhishek Pramanik, Jaya Gupta, Navin Singh, Lex Rutten, G. R. Reddy |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
education.field_of_study
medicine.medical_specialty Prognostic factor biology business.industry Population Headache Lesser known homoeopathic medicines lcsh:RX1-681 Homeopathy biology.organism_classification Predictive value Likelihood ratio Confidence interval Clinical study Complementary and alternative medicine lcsh:Homeopathy Internal medicine Medicine Observational study Gymnema sylvestre business education Allium sativum |
| Zdroj: | Indian Journal of Research in Homoeopathy, Vol 13, Iss 1, Pp 4-11 (2019) |
| ISSN: | 0974-7168 |
| Popis: | Aim: Assessment of group-confined likelihood ratio (GCLR) for the symptom ‘Headache’ from among 20 lesser-known remedies clinically verified by the Central Council for Research in Homoeopathy during the period 2012–2018. Materials and Methods: Analysis of data of the clinical verification study, which was a multicentric, open-label, observational clinical study conducted at 13 study sites of the council. The 50 medicines that completed the drug proving programme of the council were clinically verified in ascending potencies of 6C, 30C and 200C. Of these, 20 lesser-known medicines allowed analysis of the prevalence and LR of the symptom ‘Headache'. These 20 medicines were ordered according to the prevalence of headache, and LR >1 gave an indication what medicines were more related to headache than others. Results: The symptom ‘Headache’ was recorded in a part of the population: 4582 patients where 20 lesser-known medicines were prescribed. Of these medicines, 8 have a GCLR >1, indicating that the symptom headache could indicate these medicines out of the assessed group of 20. Only 5 had statistically significant confidence interval: Allium sativum, Formicum acidum, Gymnema sylvestre, Avena sativa and Persea americana. Among these, two medicines, Allium sativum and Formicum acidum, have significantly higher GCLR. Conclusion: Of 20 lesser-known homeopathic medicines, two could be considered for the further evaluation of the relationship with headache. These findings should be confirmed in properly organised prognostic factor research in a larger population, not restricted to specific medicines, that enables proper comparison. |
| Databáze: | OpenAIRE |
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