Gold-Catalyzed Intramolecular Cyclization of N-Propargylic β-Enaminones for the Synthesis of 1,4-Oxazepine Derivatives

Autor:	Balasubramanian Sridhar, Surisetti Suresh, Ravirala Narender, Desamala Ashok Kumar, Galla V. Karunakar, Kommuru Goutham
Rok vydání:	2015
Předmět:	chemistry.chemical_compound Chemistry Organic Chemistry Intramolecular cyclization Oxazepine Medicinal chemistry Radical cyclization Catalysis
Zdroj:	The Journal of Organic Chemistry. 80:11162-11168
ISSN:	1520-6904 0022-3263
Popis:	An efficient and mild one-pot, gold-catalyzed intramolecular cyclization of N-propargylic β-enaminones has been achieved for the generation of 1,4-oxazepine derivatives. This synthetic transformation tolerates a range of substituted N-propargylic β-enaminones in moderate to good yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b173eeb597931a9bf4169b388ccc0dc0 https://doi.org/10.1021/acs.joc.5b01733 Zobrazit plný text záznamu