The avian pecten provides a potent substrate for growth and development of dissociated embryonic neural implants
| Autor: | Joe Zappia, David Ehrlich, Jintana Sattayasai, Chandan J. Gurusinghe |
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| Rok vydání: | 1987 |
| Předmět: |
Superior Colliculi
Retina animal structures Graft Survival Retinal Vessels Embryo Chick Embryo Pecten (biology) Anatomy Biology Eye Vitreous Body Transplantation Microscopy Electron Brain implant medicine.anatomical_structure Developmental Neuroscience Synapses Ultrastructure Neuropil medicine Animals sense organs Implant Developmental Biology |
| Zdroj: | Developmental Brain Research. 33:139-144 |
| ISSN: | 0165-3806 |
| DOI: | 10.1016/0165-3806(87)90184-2 |
| Popis: | A cell suspension of the optic tecta of 3-day-old chick embryos was injected into the vitreal chamber of 2-day-old posthatch chicks. After a 14-21-day survival period, examination of eyeballs showed that all implants survived and, in 50% of cases, were attached to the pecten. The implants had proliferated and showed a laminated pattern of organization, with small cells in the superficial regions and large cells in the deep regions of the implant. The implants also contained a well-developed neuropil with mature synapses. The host retina was not affected by the presence of the implant. We suggest that the avian pecten represents a highly amenable structure for studies involving the response(s) by damaged retinae to neural implants. |
| Databáze: | OpenAIRE |
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