Apophysomyces variabilis, an emerging and worrisome cause of primary cutaneous necrotizing infections in India

Autor: Alberto M. Stchigel, Josep Guarro, Nidhi Singla, Jagdish Chander, Ashok K. Attri, Rps Punia, Mandeep Kaur, José F. Cano-Lira, Ana Alastruey-Izquierdo
Rok vydání: 2021
Předmět:
Zdroj: Journal of Medical Mycology. 31:101197
ISSN: 1156-5233
DOI: 10.1016/j.mycmed.2021.101197
Popis: In India, Apophysomyces species complex is the second common agent of mucormycosis mainly affecting immunocompetent hosts unlike other Mucorales. It is frequently involved in causing necrotizing cutaneous infections. The present two-year study was planned to investigate the causative role of Apophysomyces spp. in cutaneous necrotizing infections. The tissue samples were processed using standard techniques and in five out of 65 patients, Apophysomyces variabilis was the etiological agent. Diabetes mellitus and trauma were common risk factors and despite appropriate treatment only one patient could be survived. Apophysomyces variabilis is emerging as agent of necrotizing infections which invariably result in poor patient outcomes.
Databáze: OpenAIRE