| Autor: |
James Luccarelli, Brent P. Forester, Mary Dooley, Regan E. Patrick, David G. Harper, Stephen J. Seiner, Georgios Petrides, Martina Mueller, Michael E. Henry |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Am J Geriatr Psychiatry |
| ISSN: |
1064-7481 |
| DOI: |
10.1016/j.jagp.2021.12.008 |
| Popis: |
OBJECTIVES: This study explores the association between baseline impaired global cognitive function and changes in global cognitive function and depression among geriatric patients undergoing acute course electroconvulsive therapy (ECT). DESIGN: Retrospective cohort study SETTING: Single freestanding psychiatric hospital PARTICIPANTS: Patients aged 50 and older receiving ECT INTERVENTIONS: 10 ECT treatments MEASUREMENTS: Cognitive assessments with the Montreal Cognitive Assessment (MoCA). Depression assessment with the Quick Inventory of Depressive Symptomatology Self Report 16 item scale (QIDS) RESULTS: Baseline and follow-up data were available for 684 patients. On average, patients with baseline normal cognition (MoCA ≥ 26; N = 371) had a decrease in MoCA of −1.44 ±0.26 points over the course of treatment, while those with baseline impaired global cognitive function (MoCA < 26; N = 313) had an increase in MoCA of 1.72±0.25 points. Baseline cognitive status was not associated with a differential response on the QIDS. CONCLUSIONS: Patients with baseline impaired global cognitive function did not demonstrate a worsening in cognition following ECT, and baseline global cognitive function was not associated with a differential change in depression with ECT. These results suggest that impaired global cognitive function should not be viewed as a contraindication to ECT in geriatric patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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