Healing of Muscle-Pedicle Bone Grafts: An Experimental Study

Autor: Sandor Medgyesi
Rok vydání: 1965
Předmět:
Zdroj: Acta Orthopaedica Scandinavica. 35:294-299
ISSN: 0001-6470
DOI: 10.3109/17453676508989360
Popis: A muscle-pedicle graft receives its blood supply through a softtissue pedicle, so that grafting over a fairly short distance ought to be compatible with the survival of some of its cells. The graft may be compact or cancellous, and the pedicle usually consists of a muscle and tendon or subcutaneous tissue and skin, depending on the donor site. In a previous paper (1) the reported clinical and experimental studies on muscle-pedicle bone grafts were reviewed. Only a few experimental studies have been published (2,3,4 and 7), and the results have differed. Our results are among the positive ones, and the present study marks a further step forward in the series. This time, the transplantation was performed in a way which eliminated the osteogenetic activity of the recipient site in order to assess the role of the graft itself in the healing process. The method was as follows: The experimental animals were white rabbits weighing 2.5-3.5 kg. The rabbits were mature, but in some of them the epiphyseal cartilage could be discerned. The operation was carried out under Nembutal anaesthesia. A graft, 10 X 5 X 5 mm, was removed from the greater trochanter on both sides. The pedicle consisted of half the gluteus medius and minimus which were dissected to a length of 1 cm. From the iliac crest a somewhat larger piece of bone was removed, freed entirely and denuded of muscle tissue. The pedicle grafts and the pieces of bane were tied together with a silk Aided by a grant from the Danish Science Foundation.
Databáze: OpenAIRE