Occurrence of symptoms in different stages of Duchenne muscular dystrophy and their impact on social participation
| Autor: | Jan J.G.M. Verschuuren, Jos G.M. Hendriksen, Lotte Heutinck, Edith H. C. Cup, Erik H. Niks, Imelda J. M. de Groot, Yvonne D. Krom, Michèl A.A.P. Willemsen, Saskia L.S. Houwen-van Opstal, Merel Jansen |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Duchenne muscular dystrophy myalgia social participation medicine.medical_specialty Physiology Disease Young Adult Cellular and Molecular Neuroscience Surveys and Questionnaires Physiology (medical) Internal medicine medicine Humans Medical diagnosis Muscle contracture business.industry aging Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3] medicine.disease Social engagement Muscular Dystrophy Duchenne signs and symptoms Cross-Sectional Studies Blood pressure Life expectancy symptoms Self Report Neurology (clinical) medicine.symptom business |
| Zdroj: | Muscle & Nerve, 64(6), 701-709. WILEY Muscle and Nerve, 64, 6, pp. 701-709 Muscle and Nerve, 64, 701-709 |
| ISSN: | 1097-4598 0148-639X |
| Popis: | Contains fulltext : 244841.pdf (Publisher’s version ) (Open Access) INTRODUCTION/AIMS: As life expectancy improves for patients with Duchenne muscular dystrophy (DMD), new symptoms are likely to arise. This aims of this study are: (1) to explore the prevalence of a broad variety of symptoms in the various stages of DMD (with and without steroid use); (2) to explore the prevalence of common secondary diagnoses; and (3) to evaluate the social participation level of patients with DMD older than 16 y of age; and to explore correlations between social participation and symptoms. METHODS: A cross-sectional self-report questionnaire, including questions on functional level and health status, as well as a standardized participation scale was distributed among Dutch patients with DMD. RESULTS: Eighty-four male patients with a mean age of 22.0 (SD = 10.0) y were enrolled. The most prevalent and limiting symptoms were difficulty coughing (58%), coldness of hands (57%), contractures (51%), stiffness (49%), fatigue (40%), myalgia (38%), and low speech volume (33%). Prevalent secondary diagnoses included cardiac disease (14%), neurobehavioral diagnosis (13%), low blood pressure (13%), and arthrosis (5%). Social participation correlated negatively with coldness of hands (r = - .29; P |
| Databáze: | OpenAIRE |
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