Additional file 1 of Pan-cancer analysis of whole-genome doubling and its association with patient prognosis

Autor: Kikutake, Chie, Suyama, Mikita
Rok vydání: 2023
DOI: 10.6084/m9.figshare.23621296.v1
Popis: Additional file 1: Supplementary Figure S1. The proportion of samples with LOH in each chromosome and TSG and essential gene distribution. Supplementary Figure S2. The ratio of early clonal indel density within the LOH region to that outside the LOH region in WGD samples and the ratio of clonal indel density within the LOH region to that outside the LOH region in nWGD samples. Supplementary Figure S3. Early mutation accumulation in genes within the LOH region. Supplementary Figure S4. The ratio of late clonal and subclonal indel density within the LOH region to that outside the LOH region in WGD samples and the ratio of subclonal indel density within the LOH region to that outside the LOH region in nWGD samples. Supplementary Figure S5. Late mutation accumulation in genes within the LOH region. Supplementary Figure S6. Survival analysis using WGD occurrence-associated factors in case of early mutations based on TCGA data. Supplementary Figure S7. Survival analysis using WGD occurrence-associated factors in case of late mutations. Supplementary Figure S8. Survival analysis using WGD occurrence-associated factors in case of late mutations based on TCGA data. Supplementary Figure S9. Prognostic gene exploration using PCAWG data. Supplementary Figure S10. Association between AXIN1 in the LOH region and prognosis in WGD samples using PCAWG data. Supplementary Figure S11. Extracted prognosis-related genes in the 16p.13.3 locus. Supplementary Figure S12. Number of samples with prognosis-related TSGs in the LOH region of WGD samples using PCAWG data. Supplementary Figure S13. Association between PTEN mutations in LOH and prognosis in nWGD samples using PCAWG data.
Databáze: OpenAIRE