| Autor: |
Mark Basik, Jacek Majewski, Catalin Mihalcioiu, Elizabeth A. Marcus, André Robidoux, Josée-Anne Roy, Peter Tonellato, Sheida Nabavi, Eric Bareke, Christoph H. Borchers, René P. Zahedi, Vincent R. Richard, Stephen D. Hursting, Ciara O'Flanagan, Sylvia Josephy, Horace Uri Saragovi, Moulay Alaoui-Jamali, Amine Saad, Naciba Benlimame, Marie-Christine Guilbert, Cristiano Ferrario, Olga Aleynikova, Luca Cavallone, Urszula Krzemien, Cathy Lan, Ewa Przybytkowski, Stéphanie Légaré, Banujan Balachandran, Aparna Ramanathan, Catherine Chabot, Marguerite Buchanan, Michelle Scriver, Viet Vu, Emma Fowler, Josiane Lafleur, Adriana Aguilar-Mahecha, Isabelle Sirois |
| Rok vydání: |
2023 |
| Popis: |
Table S1: List of regions of genes with increased CNV (>= 0.5) and gene expression (>= 0.5) in DOXO-R cells compared to parental cells Table S2: List of all fold change and pvalue of DOXO-R C1 and C8 (vs parental cells) from gene expression analysis. Table S3. GSEA using the C5 module for the 1852 genes with gene expression fold change > 1.5 (pval < 0.05) in DOXO-R C1 and C8 Table S4. GSEA using the C5 module for the 407 genes with gene expression fold change > 1.5 (pval < 0.05) and CNV change > 0.5 Table S5: Mean LOG2FC of genes commonly up-regulated in C1 and C8 Table S6: Proteins that are significantly upregulated according to the following criteria. (i) only present in one or two of the Dox resistant cell lines (**) with at least 3 and 2 unique peptides, respectively. (ii) At least 1.5-fold upregulated in both cell lines with a maximum relative standard deviation (RSD) of 31% across control replicates and 25% RSD across resistant cell line replicates. Table S7: GSEA using the C5 module for the 98 overexpressed proteins in DOXO-R vs parental cells Table S8: mRNA fold change (POST vs PRE NAC) for 9 chemoresistant TNBC patients. Table S9: GSEA using the C5 module for NEO2 up regulated genes > 2.5 FC. The complete list of genes are listed below the GSEA analysis. Table S10: GSEA using the C5 module for NEO24 up regulated genes > 2.5 FC. The complete list of genes are listed below the GSEA analysis. Table S11: GSEA using the C5 module for NEO25 up regulated genes > 2.5 FC. The complete list of genes are listed below the GSEA analysis. Table S12: GSEA using the C5 module for NEO27 up regulated genes > 2.5 FC. The complete list of genes are listed below the GSEA analysis. Table S13: GSEA using the C5 module for NEO28 up regulated genes > 2.5 FC. The complete list of genes are listed below the GSEA analysis. Table S14: GSEA using the C5 module for NEO30 up regulated genes > 2.5 FC. The complete list of genes are listed below the GSEA analysis. Table S15: GSEA using the C5 module for NEO31 up regulated genes > 2.5 FC. The complete list of genes are listed below the GSEA analysis. Table S16: GSEA using the C5 module for NEO35 up regulated genes > 2.5 FC. The complete list of genes are listed below the GSEA analysis. Table S17: GSEA using the C5 module for NEO44 up regulated genes > 2.5 FC. The complete list of genes are listed below the GSEA analysis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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