Very delayed liver metastasis from small bowel gastrointestinal stromal tumor (32 years after resection of the small bowel GIST): Report of a case
| Autor: | Osamu Honda, Futoshi Uno, Ryosuke Yoshida, Masahiro Ishizaki, Shunsaku Miyauchi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Leiomyosarcoma
medicine.medical_specialty medicine.medical_treatment Case Report Resection Metastasis Late liver metastasis 03 medical and health sciences 0302 clinical medicine Biopsy medicine Stromal tumor medicine.diagnostic_test GiST business.industry Follow up medicine.disease Small intestine medicine.anatomical_structure 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Surgery Radiology Hepatectomy business GIST |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| Popis: | Highlights • This is a case with the longest disease free interval after GIST surgery before metastasis to the liver. • Late liver metastasis can occur in the low risk group. • Our case was in the low risk group as per the Modified-Fletcher classification. Introduction Recurrent forms of gastrointestinal stromal tumor (GIST) include liver metastases and peritoneal dissemination. Recurrence often occurs within 2 years. We report a case of liver metastasis, which was detected 30 years after resection of a primary lesion in the small intestine and was resected 32 years later. Presentation of case The patient was a 72-year-old woman and was being followed up for ureteral stones at the department of urology of our hospital. Computed tomography (CT) showed a small mass in segment 7 of the liver, 2 years ago. As the tumor gradually increased, a biopsy was performed, and a mesenchymal tumor was diagnosed. The tumor continued to increase in size and partial hepatectomy was performed. GIST was suspected from the sample extracted during hepatectomy. The patient had undergone a resection of the small intestine for a tumor 32 years ago. On tracing her medical records, it was confirmed that resection of the small intestine was performed for the diagnosis of leiomyosarcoma. Discussion Based on the block specimen from 32 years ago, the tumor of the intestine was confirmed to be GIST, and the liver mass was finally diagnosed as liver metastasis of the GIST that had occurred 32 years ago. Conclusion We experienced a case of liver metastasis 32 years after surgery for the first small intestinal GIST. To the best of our knowledge, this case had the longest disease-free interval before metastasis to the liver. |
| Databáze: | OpenAIRE |
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