Recycling of 3He from lung magnetic resonance imaging
Autor: | S. Karpuk, Zahir Salhi, Ursula Wolf, Ernst W. Otten, M. Gueldner, D. Rudersdorf, Reinhard Surkau, Werner Heil, T. Großmann |
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Rok vydání: | 2011 |
Předmět: |
Leak
business.product_category Contrast Media chemistry.chemical_element Molecular sieve Helium Adsorption Isotopes Getter Impurity Administration Inhalation Bottle medicine Humans Recycling Radiology Nuclear Medicine and imaging Lung Chromatography medicine.diagnostic_test Chemistry Magnetic resonance imaging Equipment Design Magnetic Resonance Imaging Equipment Failure Analysis Exhalation Radiopharmaceuticals business |
Zdroj: | Magnetic Resonance in Medicine. 67:1758-1763 |
ISSN: | 0740-3194 |
DOI: | 10.1002/mrm.23154 |
Popis: | We have developed the means to recycle 3He exhaled by patients after imaging the lungs using magnetic resonance of hyperpolarized 3He. The exhaled gas is collected in a helium leak proof bag and further compressed into a steel bottle. The collected gas contains about 1–2% of 3He, depending on the amount administered and the number of breaths collected to wash out the 3He gas from the lungs. 3He is separated from the exhaled air using zeolite molecular sieve adsorbent at 77 K followed by a cold head at 8 K. Residual gaseous impurities are finally absorbed by a commercial nonevaporative getter. The recycled 3He gas features high purity, which is required for repolarization by metastability exchange optical pumping. At present, we achieve a collection efficiency of 80–84% for exhaled gas from healthy volunteers and cryogenic separation efficiency of 95%. Magn Reson Med, 2011. © 2011 Wiley-Liss, Inc. |
Databáze: | OpenAIRE |
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