Antimicrobial activities of indole alkaloids from Tabernaemontana catharinensis

Autor:	Luiz Afonso de Melo Prado, Sérgio Souza Figueiredo, Ana Lúcia Fachin, Nilce Maria Martinez-Rossi, Juliana da Silva Coppede, V.C. Fernandes, Maria Rita Furquini Medeiros, Rene Oliveira Beleboni, Giovana Maria Lanchoti Fiori, Juliana Simões Martins, Silvia Helena Taleb Contini, Paulo Pereira
Rok vydání:	2011
Předmět:	Pharmacology Citrobacter biology Chemistry Plant Extracts Tabernaemontana Alkaloid Klebsiella oxytoca Plant Science General Medicine Trichophyton rubrum Microbial Sensitivity Tests Tabernaemontana catharinensis Antimicrobial medicine.disease_cause biology.organism_classification Microbiology Indole Alkaloids Complementary and alternative medicine Anti-Infective Agents Drug Discovery Dermatophyte medicine Antibacterial activity
Zdroj:	Natural product communications. 6(2)
ISSN:	1934-578X
Popis:	Tabernaemontana catharinensis root bark ethanol extract, EB2 fraction and the MMV alkaloid (12-methoxy-4-methylvoachalotine) were evaluated for their antimicrobial activities. T. catharinensis ethanol extract was effective against both strains of the dermatophyte Trichophyton rubrum at concentrations of 2.5 mg/mL (wild strain) and 1.25 mg/mL (mutant strain), while the EB2 fraction and MMV alkaloid showed a strong antifungal activity against wild and mutant strains with MIC values of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13e6b3f980c1d727eb58359fb243e64 https://pubmed.ncbi.nlm.nih.gov/21425672 Zobrazit plný text záznamu