Oocyte yield in social, medical and donor oocyte cryopreservation cycles
| Autor: | Lorraine Kasaven, Paul Serhal, Srdjan Saso, Ephia Yasmin, Aviva Petrie, Rabi Odia, Guy Norris, J Ben-Nagi, Joycelia Green, Benjamin P Jones |
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| Rok vydání: | 2020 |
| Předmět: |
Cryopreservation
030219 obstetrics & reproductive medicine Estradiol Oocyte Donation Oocyte Retrieval Obstetrics and Gynecology Donor oocyte 030209 endocrinology & metabolism General Medicine Biology Oocyte Andrology 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Reproductive Medicine Oocyte donation Yield (chemistry) Oocytes medicine Humans Female Vitrification Retrospective Studies |
| Zdroj: | Human Fertility. 25:508-515 |
| ISSN: | 1742-8149 1464-7273 |
| DOI: | 10.1080/14647273.2020.1855369 |
| Popis: | To determine if oocyte yield in women undergoing cryopreservation for social (SOC), medical (MOC) and oocyte donation (OD) cycles is comparable when matched for age. 315 oocyte retrievals were performed for SOC, 116 for MOC and 392 for OD. Non-parametric Kruskal-Wallis tests and Poisson regression were used to assess the impact of age stratification. The median ages of women undergoing SOC, MOC, and OD were 38, 31 and 26 years respectively. The median (IQR) number of oocytes in the three categories was 7, 10, and 12. The oocyte yield was significantly higher in women aged 30-34 years undergoing SOC, compared to the MOC group. For the SOC group, age in years, oestradiol levels per 1000 pmol/and follicle count12mm on the day of trigger were significant predictors of oocyte yield. Women embarking on SOC are significantly older than those undergoing MOC and OD, and thus oocyte yield is reduced when stratified for age. This study highlights the significant predictors of oocyte yield amongst women undergoing oocyte cryopreservation for specific indications. The findings can be used to optimise the yield and overall chance of successful livebirth. |
| Databáze: | OpenAIRE |
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