Relative transmissibility of shigellosis among male and female individuals: a modeling study in Hubei Province, China

Autor: Yao Wang, Xiaokun Liu, Ran An, Zeyu Zhao, Ning Wang, Qi Chen, Yingying Su, Tianmu Chen, Yi-Chen Chiang, Mei-Jie Chu, Jia Rui, Lili Pan, Bin Zhao, Mikah Ngwanguong Hannah, Benhua Zhao, Shanshan Yu, Xianfa Xuan, Yingbin Wang
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
Male
medicine.medical_specialty
Shigellosis
China
Adolescent
030231 tropical medicine
law.invention
Disease Outbreaks
lcsh:Infectious and parasitic diseases
03 medical and health sciences
Young Adult
0302 clinical medicine
Age Distribution
Mathematical model
law
medicine
Humans
lcsh:RC109-216
030212 general & internal medicine
Transmission risks and rates
Sex Distribution
Child
Disease burden
Aged
Dysentery
Bacillary
business.industry
Transmissibility
Public health
Incidence
lcsh:Public aspects of medicine
Public Health
Environmental and Occupational Health
Gender
lcsh:RA1-1270
General Medicine
Middle Aged
Models
Theoretical
medicine.disease
Disease control
Transmissibility (vibration)
Infectious Diseases
Transmission (mechanics)
Tropical medicine
Female
Shigella
business
Demography
Research Article
Zdroj: Infectious Diseases of Poverty, Vol 9, Iss 1, Pp 1-16 (2020)
Infectious Diseases of Poverty
ISSN: 2049-9957
Popis: BackgroundDeveloping countries exhibit a high disease burden from shigellosis. Owing to the different incidences in males and females, this study aims to analyze the features involved in the transmission of shigellosis among male (subscriptm) and female (subscriptf) individuals using a newly developed sex-based model.MethodsThe data of reported shigellosis cases were collected from the China Information System for Disease Control and Prevention in Hubei Province from 2005 to 2017. A sex-based Susceptible–Exposed–Infectious/Asymptomatic–Recovered (SEIAR) model was applied to explore the dataset, and a sex-age-based SEIAR model was applied in 2010 to explore the sex- and age-specific transmissions.ResultsFrom 2005 to 2017, 130 770 shigellosis cases (including 73 981 male and 56 789 female cases) were reported in Hubei Province. The SEIAR model exhibited a significant fitting effect with the shigellosis data (P 8forSARmm(secondary attack rate from male to male), 2.5729 × 108forSARmf, 2.7630 × 10-8forSARfm, and 2.1061 × 10-8forSARff. The top five mean values of the transmission relative rate in 2010 (where the subscript 1 was defined as male and age ≤ 5 years, 2 was male and age 6 to 59 years, 3 was male and age ≥ 60 years, 4 was female and age ≤ 5 years, 5 was female and age 6 to 59 years, and 6 was male and age ≥ 60 years) were 5.76 × 10-8forβ61, 5.32 × 10-8forβ31, 4.01 × 10-8forβ34, 7.52 × 10-9forβ62, and 6.04 × 10-9forβ64.ConclusionsThe transmissibility of shigellosis differed among male and female individuals. The transmissibility between the genders was higher than that within the genders, particularly female-to-male transmission. The most important route in children (age ≤ 5 years) was transmission from the elderly (age ≥ 60 years). Therefore, the greatest interventions should be applied in females and the elderly.
Databáze: OpenAIRE
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