Effects of ozone therapy on haemostatic and oxidative stress index in coronary artery disease
| Autor: | Livan Delgado-Roche, Gregorio Martínez-Sánchez, Lamberto Re, Gema Pérez-Davison, Arquímides Díaz-Batista |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Coronary Artery Disease medicine.disease_cause Gastroenterology Sudden death Antioxidants Coronary artery disease Ozone Lipid oxidation Internal medicine Antithrombotic Medicine Humans Policosanol Aged Pharmacology Aged 80 and over Aspirin Hemostasis business.industry Middle Aged medicine.disease Ozone therapy Surgery Oxidative Stress Female Fatty Alcohols business Reactive Oxygen Species Oxidative stress Biomarkers medicine.drug |
| Zdroj: | European journal of pharmacology. 691(1-3) |
| ISSN: | 1879-0712 |
| Popis: | Coronary artery disease (CAD) is the most common cause of sudden death, and death of people over 20 years of age. Because ozone therapy can activate the antioxidant system and improve blood circulation and oxygen delivery to tissue, the aim of this study was to investigate the therapeutic efficacy of ozone in patients with CAD, treated with antithrombotic therapy, Aspirin and policosanol. A randomized controlled clinical trial was performed with 53 patients divided into two groups: one (n=27) treated with antithrombotic therapy and other (n=26) treated with antithrombotic therapy plus rectal insufflation of O(3). A parallel group (n=50) age and gender matched was used as reference for the experimental variables. The efficacy of the treatments was evaluated by comparing hemostatic indexes and biochemical markers of oxidative stress in both groups after 20 day of treatment. Ozone treatment significantly (P |
| Databáze: | OpenAIRE |
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