Cutting needle biopsy in the diagnosis of clinically suspected non-carcinomatous disease of the lung
Autor: | Fergus V. Gleeson, Z C Traill, P J Haggett, H K Bungay, R F Adams, C M Morris |
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Rok vydání: | 2000 |
Předmět: |
Adult
Lung Diseases Male medicine.medical_specialty Lung Neoplasms Percutaneous Lymphoma Lung biopsy Diagnosis Differential Lesion Biopsy medicine Carcinoma Humans Radiology Nuclear Medicine and imaging Aged Retrospective Studies Lung medicine.diagnostic_test business.industry Biopsy Needle Respiratory disease General Medicine Adenocarcinoma Bronchiolo-Alveolar Middle Aged medicine.disease Surgery Radiography medicine.anatomical_structure Fine-needle aspiration Female Radiology medicine.symptom business |
Zdroj: | The British Journal of Radiology. 73:349-355 |
ISSN: | 1748-880X 0007-1285 |
DOI: | 10.1259/bjr.73.868.10844858 |
Popis: | Most patients referred for lung biopsy have a focal lesion that is likely to be a carcinoma, and fine needle aspiration is usually sufficient to confirm the diagnosis. When non-carcinomatous disease is suspected, tissue architecture is important and potential diagnostic techniques include percutaneous cutting needle biopsy (CNB). We retrospectively reviewed 37 CNBs performed for clinically suspected non-carcinomatous disease; recording the biopsy result, final diagnosis, radiological nature of the pulmonary abnormality, distance from the pleura of the lesion biopsied and biopsy complications. 9 patients had a single pulmonary nodule/mass; 13 had multiple nodules/masses; 8 had a lobar consolidation/mass; and 7 had multifocal consolidation. The lesion abutted the pleura in 31 cases, lying within 1 cm in the other 6 cases. The minor complication rate was 14%, with no major complications. Specific malignant diagnoses were made in 9 patients, and specific benign in 23, in all of whom clinicoradiological follow-up was concordant. CNB did not yield a specific diagnosis in five patients, including two lymphomas and one case of unsuspected tuberculosis in which the sample was not cultured. The overall accuracy of CNB was 32/37 (86%). CNB is a safe and accurate means of achieving a tissue diagnosis for patients with peripheral pulmonary parenchymal disease thought not to represent carcinoma. |
Databáze: | OpenAIRE |
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