Effects of gestational age at delivery and type of labor on neonatal outcomes among infants with gastroschisis†
| Autor: | Yair J. Blumenfeld, Elizabeth Fluharty, Karl G. Sylvester, Katie Sherwin, Anna I. Girsen, Alexis S. Davis, Bryan T. Oshiro, Trina Mansour, Paula Trepman, Susan R. Hintz, Arti K. Desai |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Gestational Age 03 medical and health sciences Obstetric Labor Premature 0302 clinical medicine Pregnancy medicine Humans 030212 general & internal medicine Child Preterm delivery Retrospective Studies Gastroschisis Labor Obstetric 030219 obstetrics & reproductive medicine Obstetrics business.industry Infant Newborn Infant Obstetrics and Gynecology Gestational age Spontaneous labor medicine.disease Neonatal outcomes Pediatrics Perinatology and Child Health Female business |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 34:2041-2046 |
| ISSN: | 1476-4954 1476-7058 |
| DOI: | 10.1080/14767058.2019.1656191 |
| Popis: | To investigate the effect of preterm gestational age (GA) on neonatal outcomes of gastroschisis and to compare the neonatal outcomes after spontaneous labor versus iatrogenic delivery both in the preterm and early term gestational periods.A retrospective study of prenatally diagnosed gastroschisis cases born at Loma Linda University Medical Center and Lucile Packard Children's Hospital (Loma Linda, CA) between January 2009 and October 2016. A total of 194 prenatally diagnosed gastroschisis cases were identified and included in the analysis. We compared infants delivered37 0/7 to those ≥37 0/7 weeks' gestation. Adverse neonatal outcome was defined as any of: sepsis, short bowel syndrome, prolonged ventilation, or death. Prolonged length of stay (LOS) was defined as ≥75th percentile value. Outcomes following spontaneous versus iatrogenic delivery were compared. Analyses were performed using chi-squared test or Fisher's exact test for categorical variables, and Student'sOne hundred and six neonates were born37 weeks and 88 at ≥37 weeks. Adverse outcome was statistically similar among those born37 weeks compared to ≥37 weeks (48 versus 34%,Neonates with gastroschisis delivered37 weeks had prolonged LOS whereas the rate of adverse neonatal outcomes was similar between those delivered preterm versus term. Neonates born after spontaneous preterm labor had a higher rate of bowel atresia compared to those born after planned iatrogenic preterm delivery. |
| Databáze: | OpenAIRE |
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