The epidemiology, diagnosis, and management of aristolochic acid nephropathy: a narrative review
| Autor: | Graham M. Lord, David H. Phillips, Jean-Pierre Cosyns, Monique S. J. Simmonds, Marie Stiborová, H. Terence Cook, Volker M. Arlt, M. Refik Gökmen, Jean-Louis Vanherweghem, Heinz H Schmeiser, Joëlle Nortier |
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| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Pathology Urologic Neoplasms Balkan Nephropathy Aristolochic acid Disease chemistry.chemical_compound Balkan endemic nephropathy Kidney Diseases -- chemically induced -- diagnosis -- epidemiology -- physiopathology -- therapy Risk Factors Epidemiology Internal Medicine medicine Humans Intensive care medicine Aristolochic Acids -- adverse effects Plant Preparations -- adverse effects business.industry Aristolochic acid nephropathy Médecine pathologie humaine Toxicologie [toxines] General Medicine Chinese herbs medicine.disease Sciences biomédicales chemistry Cohort Urologic Neoplasms -- chemically induced -- diagnosis -- epidemiology -- physiopathology -- therapy Aristolochic Acids Narrative review Kidney Diseases Plant Preparations Balkan Nephropathy -- chemically induced -- diagnosis -- epidemiology -- therapy business |
| Zdroj: | Annals of internal medicine, 158 (6 |
| ISSN: | 1539-3704 |
| Popis: | It has been 20 years since the first description of a rapidly progressive renal disease that is associated with the consumption of Chinese herbs containing aristolochic acid (AA) and is now termed aristolochic acid nephropathy (AAN). Recent data have shown that AA is also the primary causative agent in Balkan endemic nephropathy and associated urothelial cancer. Aristolochic acid nephropathy is associated with a high long-term risk for renal failure and urothelial cancer, and the potential worldwide population exposure is enormous. This evidence-based review of the diagnostic approach to and management of AAN draws on the authors' experience with the largest and longest-studied combined cohort of patients with this condition. It is hoped that a better understanding of the importance of this underrecognized and severe condition will improve epidemiologic, preventive, and therapeutic strategies to reduce the global burden of this disease. Journal Article Research Support, Non-U.S. Gov't Review SCOPUS: re.j info:eu-repo/semantics/published |
| Databáze: | OpenAIRE |
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