Systematic Review and Meta-analysis of Blood Glucose Response to High-intensity Interval Exercise in Adults With Type 1 Diabetes

Autor: Reid D. McClure, Francisco Javier Alcántara-Cordero, Emma Weseen, Miranda Maldaner, Sarah Hart, Corbin Nitz, Normand G. Boulé, Jane E. Yardley
Rok vydání: 2023
Předmět:
Zdroj: Canadian Journal of Diabetes. 47:171-179
ISSN: 1499-2671
DOI: 10.1016/j.jcjd.2022.11.006
Popis: Exercise-induced hyperglycemia is recognized in type 1 diabetes (T1D) clinical guidelines, but its association with high-intensity intermittent exercise (HIIE) in acute studies is inconsistent. In this meta-analysis we examined the available evidence of blood glucose responses to HIIE in adults with T1D. The secondary aim was to examine predictors of blood glucose responses to HIIE. We hypothesized that there would be no consistent effect on blood glucose from HIIE, unless examined in the context of participant prandial status.We conducted a literature search using keywords related to T1D and HIIE. Studies were required to include at least 6 participants with T1D with a mean age18 years, involve an HIIE intervention and contain pre- and postexercise measures of blood glucose. Analyses of extracted data were performed using a general inverse variance statistical method with a random effects model and a weighted multiple regression.Nineteen interventions from 15 reports were included in the analysis. A mean overall blood glucose decrease of -1.3 mmol/L (95% confidence interval [CI], -2.3 to -0.2 mmol/L) was found during exercise, albeit with high heterogeneity (IThe effect of HIIE on blood glucose is inconsistent, but partially explained by prandial status.
Databáze: OpenAIRE