Capillary gas-liquid chromatography separation of phenethylamines in amphetamine-positive urine samples
| Autor: | Karl Verebey, Mahmoud A. ElSohly, Ann DePace |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Ephedrine
Chromatography Chromatography Gas medicine.diagnostic_test Chemistry Capillary action Phenethylamines Urine Mass spectrometry Pathology and Forensic Medicine Chromatographic separation Amphetamine Predictive Value of Tests Immunoassay Genetics medicine Humans Gas chromatography medicine.drug |
| Zdroj: | Journal of forensic sciences. 35(6) |
| ISSN: | 0022-1198 |
| Popis: | Good gas chromatography (GC) separation of molecules is essential for clean gas chromatography/mass spectrometry (GC/MS) confirmation of compounds. The trifluoro derivatives of ephedrine (E) and methamphetamine (MA) coelute on dimethyl silicone capillary columns, such as DB-1, which are most commonly used by chromatographers. Methods are described to separate E and MA to aid GC/MS confirmations of methamphetamine, ephedrine, or both E and MA together, whichever may be present in Enzyme Immunoassay (EIA)-analyzed amphetamine-positive urine samples. The use of the heptafluoro derivatives of E and MA on a DB-1 column, or the trifluoro derivatives of E and MA on a DB-17 column, is suggested for good gas chromatographic separation. |
| Databáze: | OpenAIRE |
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