The Effects of Synbiotic Supplementation on Body Mass Index, Metabolic and Inflammatory Biomarkers, and Appetite in Patients with Metabolic Syndrome: A Triple-Blind Randomized Controlled Trial
| Autor: | Bahram Rashidkhani, Navid Saadat, Samira Rabiei, Rahebeh Shakerhossini, Mehdi Hedayati |
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| Rok vydání: | 2018 |
| Předmět: |
Blood Glucose
Male 0301 basic medicine Appetite Synbiotics Gut flora Gastroenterology Body Mass Index law.invention 0302 clinical medicine Randomized controlled trial law Insulin Pharmacology (medical) media_common Metabolic Syndrome Nutrition and Dietetics biology digestive oral and skin physiology Fasting Middle Aged Lipids Inflammatory biomarkers C-Reactive Protein Treatment Outcome Research Design Female Inflammation Mediators Adult medicine.medical_specialty media_common.quotation_subject digestive system 03 medical and health sciences Insulin resistance Internal medicine medicine Humans Peptide YY In patient Aged 030109 nutrition & dietetics business.industry 030229 sport sciences medicine.disease biology.organism_classification Insulin Resistance Metabolic syndrome business Body mass index Biomarkers Food Science |
| Zdroj: | Journal of Dietary Supplements. 16:294-306 |
| ISSN: | 1939-022X 1939-0211 |
| Popis: | It has been shown recently that metabolic syndrome is associated with gut dysbiosis. The gut microbiota may be the main target for prevention or treatment of metabolic syndrome. We investigated the effects of synbiotic supplementation on metabolic syndrome. In this triple-blinded clinical trial, 46 Iranian patients with metabolic syndrome, from both sexes, aged 25-70 years, who fulfilled inclusion criteria were randomly categorized to receive either the synbiotic or a placebo capsule, twice a day for three months, plus a weight-loss diet using stratified random sampling based on body mass index (BMI). Each synbiotic capsule consisted of seven strains probiotic bacteria (2× 10 |
| Databáze: | OpenAIRE |
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