Symptomatic and asymptomatic chlamydial non-gonococcal urethritis in Jamaica: the potential for HIV transmission
| Autor: | M Baum, R Chout, Monica Smikle, S D King, Y Williams, Dowe G |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Male
Sexually transmitted disease Jamaica medicine.medical_specialty Gonorrhea Non-gonococcal urethritis Chlamydia trachomatis HIV Infections Dermatology urologic and male genital diseases medicine.disease_cause Asymptomatic Specimen Handling Internal medicine Disease Transmission Infectious Prevalence medicine Humans Pharmacology (medical) Urethritis Syphilis Chlamydia business.industry Public Health Environmental and Occupational Health virus diseases Chlamydia Infections medicine.disease female genital diseases and pregnancy complications Infectious Diseases Case-Control Studies Immunology HIV-1 medicine.symptom business |
| Zdroj: | International Journal of STD & AIDS. 11:187-190 |
| ISSN: | 1758-1052 0956-4624 |
| DOI: | 10.1258/0956462001915507 |
| Popis: | To determine the contribution of Chlamydia trachomatis to non-gonococcal urethritis (NGU) in men attending sexually transmitted disease (STD) clinics in Jamaica we studied men with NGU ( n = 339), and control groups including asymptomatic men who were STD contacts ( n = 61), asymptomatic men who were not STD contacts ( n = 32) and men with gonococcal urethritis (GU) ( n = 61). Urethral specimens were examined for C. trachomatis and Neisseria gonorrhoeae. Serological tests for syphilis (STS) and HIV-1 infection were also performed. C. trachomatis accounted for 63% of cases of NGU but high prevalences were also found in asymptomatic STD contacts (59%), asymptomatic STD non-contacts (78%) and men with GU (48%). The prevalence of C. trachomatis in men with GU differed significantly from that in men with NGU and asymptomatic STD non-contacts ( P < 0.05). C. trachomatis infection in men with NGU was associated with multiple sex partners (71% vs 58%; chi2=4.78; odds ratio (OR)= 1.76; P < 0.05) and previous history of gonococcal infection (83% vs 42%; chi2=59.8; OR=6.8; P < 0.0001). Concomitant infection with HIV-1 occurred in 5.2% of cases of NGU and 50% and 90%, respectively, of the HIV-positive men had chlamydia or reactive STS. As a cost effective strategy in the control of STD and HIV we recommend presumptive treatment for C. trachomatis in men seeking STD treatment in Jamaica. |
| Databáze: | OpenAIRE |
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