Echocardiographic findings in kidney transplanted Type 1 (insulin-dependent) diabetic patients with and without a pancreas transplant
| Autor: | I. Wallentin, O. Bech-Hanssen, Michael Olausson, Gudrun Nyberg |
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| Rok vydání: | 1991 |
| Předmět: |
Adult
Male medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment Diastole Renal function Pancreas transplantation Internal medicine Diabetes mellitus Internal Medicine medicine Humans Kidney transplantation Type 1 diabetes business.industry Heart medicine.disease Kidney Transplantation Transplantation Diabetes Mellitus Type 1 Echocardiography Cardiology Female Pancreas Transplantation Isovolumic relaxation time business Follow-Up Studies |
| Zdroj: | Diabetologia. 34:S128-S130 |
| ISSN: | 1432-0428 0012-186X |
| DOI: | 10.1007/bf00587638 |
| Popis: | Echocardiography with Doppler recordings was carried out in 14 Type 1 (insulin-dependent) diabetic recipients of pancreas and kidney transplants and in 14 Type 1 diabetic kidney transplanted control patients, matched for age, sex, duration of diabetes, extent of other late complications, time since transplantation, dose of prednisolone, and renal function. HbA1c was 5.5 +/- 0.6 vs 8.7 +/- 1.4% (pancreas transplanted vs kidney only). Both groups had a slight increase in interventricular septum thickness. Left ventricular mass was equal. The ejection fraction as a measure of systolic function was normal and equal, 0.71 +/- 0.05 vs 0.69 +/- 0.07. Diastolic function was also equal in two out of three parameters, isovolumic relaxation time and deceleration time. The A/E ratio, however, tended to be lower in the pancreas transplanted group, 0.94 +/- 0.20 vs 1.06 +/- 0.18 (p = 0.04). This indicates more frequent occurrence of impaired diastolic filling in the recipients of kidney only. Follow-up will show whether diastolic dysfunction increases and may be related to the increased cardiovascular mortality in kidney transplanted Type 1 diabetic patients. |
| Databáze: | OpenAIRE |
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