Fabrication of ZnO Nanoparticle-Based FET Device for Label-Free Bacteria Detection
| Autor: | Roy Paily, Siddhartha Sankar Ghosh, Ujjwol Barman, Upashi Goswami |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Detection limit
Gram-negative bacteria Materials science biology Bacteria Transistors Electronic Gram-positive bacteria Biomedical Engineering Pharmaceutical Science Medicine (miscellaneous) Bioengineering biology.organism_classification Computer Science Applications Threshold voltage Limit of Detection Nanoparticles Wafer Field-effect transistor Electrical and Electronic Engineering Zinc Oxide Biotechnology Nuclear chemistry Gram |
| Zdroj: | IEEE transactions on nanobioscience. 21(2) |
| ISSN: | 1558-2639 |
| Popis: | This paper reports fabrication and characterization of ZnO nanoparticle based Field Effect Transistor (FET) device and its application for simple, rapid and label-free bacteria detection. [Formula: see text] FET devices were fabricated by standard UV lithography technique on Si wafers. The fabricated devices consisted of ZnO nanoparticles as channel material. Characterization of such devices resulted in threshold voltage of -2 V and trans-conductance of [Formula: see text]. The interaction between ZnO nanoparticles and bacteria sample has been exploited in this study to utilize ZnO nanoparticle based FET device to successfully differentiate between gram positive and gram-negative bacteria. Gram negative bacteria sample resulted in higher output characteristics compared to that obtained with gram positive bacteria sample. This study reports sensitivity and Limit of Detection (LOD) of 9.48 nA/CFU/mL and 776 CFU/mL respectively for gram negative bacteria and 6.96 nA/CFU/mL and 665 CFU/mL for gram positive bacteria respectively. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|