Microbiome in healthy skin, update for dermatologists
Autor: | Leihong Flora Xiang, G. Gontijo, M. Sanchez Viera, Elena Araviiskaia, T. Bieber, Richard Martin, Enzo Berardesca, Brigitte Dréno |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
Allergy Microbial diversity Reviews Dermatology Review Article Biology Host tissue Microbiology 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Immune system RNA Ribosomal 16S medicine Humans Microbiome Skin integumentary system Bacteria Microbiota medicine.disease 030104 developmental biology Infectious Diseases Bacterial 16S rRNA Immunology Dermatologists |
Zdroj: | Journal of the European Academy of Dermatology and Venereology |
ISSN: | 1468-3083 0926-9959 |
Popis: | The skin is a complex barrier organ made of a symbiotic relationship between microbial communities and host tissue via complex signals provided by the innate and the adaptive immune systems. It is constantly exposed to various endogenous and exogenous factors which impact this balanced system potentially leading to inflammatory skin conditions comprising infections, allergies or autoimmune diseases. Unlike the gut and stool microbiome which has been studied and described for many years, investigations on the skin or scalp microbiome only started recently. Researchers in microbiology and dermatology started using modern methods such as pyrosequencing assays of bacterial 16S rRNA genes to identify and characterize the different microorganisms present on the skin, to evaluate the bacterial diversity and their relative abundance and to understand how microbial diversity may contribute to skin health and dermatological conditions. This article aims to provide an overview on the knowledge about the skin microbiota, the microbiome and their importance in dermatology. |
Databáze: | OpenAIRE |
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