A new pH catheter for laryngopharyngeal reflux: Normal values
| Autor: | Farnoosh Farrokhi, Srikant Muddana, Sean Casey, James C. Slaughter, C. Gaelyn Garrett, George Sun, Eric M. Hill, Michael F. Vaezi |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Percentile Supine position Esophageal pH Monitoring Manometry Normal values Ph monitoring Gastroenterology Sensitivity and Specificity Catheterization Cohort Studies Laryngopharyngeal reflux Reference Values Internal medicine Medicine Humans Esophageal Motility Disorders Prospective Studies Respiratory system Monitoring Physiologic business.industry Reflux medicine.disease Catheter Hypopharynx Otorhinolaryngology Anesthesia Gastroesophageal Reflux Female business |
| Zdroj: | The Laryngoscope. 119(8) |
| ISSN: | 1531-4995 |
| Popis: | Objectives/Hypothesis: Laryngopharyngeal reflux (LPR) represents a challenging field. Therapeutic studies of proton pump inhibitors in LPR have shown mixed results. The Restech pH catheter (Respiratory Technology Corp., San Diego, CA) is a minimally invasive device for detection of oropharyngeal acid reflux. The aim of this study was to provide normative data using this device in both distal esophagus and oropharynx. Study Design: Prospective observational study. Methods: Normal volunteers were recruited to undergo pH monitoring. A custom made longer catheter was used to assess distal esophageal pH. Oropharyngeal pH catheter was placed at the level of uvula. The distribution of % time was summarized using the 5th, 25th, 50th (median), 75th, and 95th quantiles for pH < 6, pH < 5, and pH < 4 for both upright and supine positions. Results: A total of 20 normal, healthy volunteers underwent pH monitoring for 14 to 24 hours (median 20.5 hours). The 95th percentile for % total time pH < 4, pH < 5, pH < 6 for the distal esophageal pH catheter were 4.52%, 10.91%, and 42.99%, respectively. For the oropharynx pH probe, the 95th percentile for % total time pH < 4, pH < 5, and pH < 6 were 0.02%, 2.33%, and 21.41% respectively. The 95th percentile for number of reflux events for total pH < 4, pH < 5, and pH < 6 were 1.3, 8.1, and 128.0, respectively. Conclusions: Oropharyngeal acid reflux is an infrequent occurrence in healthy volunteers without LPR. The normative data for Restech pH catheter may now be compared to those with suspected LPR. Laryngoscope, 2009 |
| Databáze: | OpenAIRE |
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