'Incidence and Clinico-Radiological Correlations of Early Arterial Reocclusion After Successful Thrombectomy in Acute Ischemic Stroke'
| Autor: | Antonio López-Rueda, Carlos Laredo, Laura Llull, Salvatore Rudilosso, Xabier Urra, Arturo Renú, Victor Obach, Sergio Amaro, Napoleon Macias, Daniel Santana, Ángel Chamorro |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Neurology Time Factors Perfusion scanning Brain Ischemia Cohort Studies 03 medical and health sciences 0302 clinical medicine Modified Rankin Scale Internal medicine medicine Humans Longitudinal Studies Aged Ischemic Stroke Thrombectomy Aged 80 and over business.industry General Neuroscience Incidence (epidemiology) Incidence Odds ratio Vascular surgery Middle Aged Magnetic Resonance Imaging Cerebrovascular Disorders 030104 developmental biology Treatment Outcome Etiology Cardiology Female Neurology (clinical) Neurosurgery Cardiology and Cardiovascular Medicine business Tomography X-Ray Computed 030217 neurology & neurosurgery Follow-Up Studies |
| Zdroj: | Translational stroke research. 11(6) |
| ISSN: | 1868-601X |
| Popis: | About half of acute stroke patients treated with mechanical thrombectomy (MT) do not show clinical improvement despite successful recanalization. Early arterial reocclusion (EAR) may be one of the causes that explain this phenomenon. We aimed to analyze the incidence and clinico-radiological correlations of EAR after successful MT. A consecutive series of patients treated with MT between 2010 and 2018 at a single-center included in a prospective registry was retrospectively reviewed. Specific inclusion criteria for the analysis were (1) successful recanalization after MT and (2) availability of pretreatment CT perfusion and follow-up MRI. EAR was evaluated in the follow-up MR angiography. Adjusted regression models were used to analyze the association of EAR with pretreatment variables, infarct growth, final infarct volume, and clinical outcome at 90 days (ordinal distribution of the modified Rankin Scale scores). Out of 831 MT performed, 218 (26%) patients fulfilled inclusion criteria, from whom 13 (6%) suffered EAR. In multivariate analysis controlled by confounders, EAR was independently associated with poor clinical outcome (aOR = 3.2, 95%CI = 1.16–9.72, p = 0.039), greater final infarct volume (aOR = 3.8, 95%CI = 1.93–7.49, p |
| Databáze: | OpenAIRE |
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