Schizophrenia polygenic risk score and long-term success in the labour market: A cohort study
| Autor: | Jutta Viinikainen, Petri Böckerman, Christian Hakulinen, Jaana T. Kari, Terho Lehtimäki, Olli T. Raitakari, Jaakko Pehkonen |
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| Přispěvatelé: | Tampere University, Department of Clinical Chemistry, Clinical Medicine, Department of Psychology and Logopedics, Helsinki Inequality Initiative (INEQ), Psychosocial factors and health, Faculty Common Matters (Faculty of Education) |
| Rok vydání: | 2022 |
| Předmět: |
Male
Employment perinnölliset taudit skitsofrenia 515 Psychology työllistyminen 3121 Internal medicine behavioral disciplines and activities 3124 Neurology and psychiatry perinnöllinen alttius Education Cohort Studies työmarkkina-asema Psychiatry and Mental health koulutustaso Polygenic risk score Risk Factors Earnings Social income transfers mental disorders Schizophrenia Educational Status Humans Biological Psychiatry |
| Zdroj: | Journal of Psychiatric Research |
| ISSN: | 0022-3956 |
| DOI: | 10.1016/j.jpsychires.2022.05.041 |
| Popis: | Publisher Copyright: © 2022 The Authors Employment is rare among people with a schizophrenia diagnosis. Meanwhile, a genetic liability for schizophrenia may hinder labour market performance. We studied how the polygenic risk score (PGS) for schizophrenia related to education and labour market outcomes. We found that a higher PGS was linked to lower educational levels and weaker labour market outcomes as well as a higher likelihood of receiving social income transfers, particularly among men. Assuming that the link is causal, our results indicate that individuals with schizophrenia or schizophrenia-related traits have a weakened ability to fully participate in the labour market, potentially reinforcing social exclusion. |
| Databáze: | OpenAIRE |
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