Infectious mononucleosis with atypical manifestations accompanied by transient IgM antibody response for cytomegalovirus
| Autor: | Takahiko Kudo, Takayoshi Miyazono, Jun Nishikawa, Toshiro Sugiyama, Hisashi Funada, Haruka Fujinami, Jun Murakami, Takako Miyazaki |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male Microbiology (medical) Herpesvirus 4 Human medicine.medical_specialty Mononucleosis Congenital cytomegalovirus infection Cytomegalovirus Biology Antibodies Viral medicine.disease_cause Virus Medical microbiology Immune system hemic and lymphatic diseases medicine Humans Pharmacology (medical) Infectious Mononucleosis medicine.disease Epstein–Barr virus Virology Infectious Diseases Immunoglobulin M Cytomegalovirus Infections Immunology biology.protein Antibody |
| Zdroj: | Journal of Infection and Chemotherapy. 17:686-688 |
| ISSN: | 1341-321X |
| DOI: | 10.1007/s10156-011-0221-6 |
| Popis: | Infectious mononucleosis (IM) is a clinical syndrome caused by primary infection with Epstein-Barr virus (EBV) that is common in adolescents. In adults, particularly in elderly people, the clinical picture of IM tends to be atypical, often leading to a diagnostic challenge. Diagnosis is also complicated because infection with EBV can induce the synthesis of cross-reacting immunoglobulin M antibodies for other herpesviruses. We report an unusual case of infectious mononucleosis in a 34-year-old immunocompetent adult. Epidemiological studies indicate that the average age of primary EBV infection in developed countries is increasing. IM with atypical presentation will be a diagnostic challenge in the future as the number of EBV-naïve adults increases. |
| Databáze: | OpenAIRE |
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