Cartilage evaluation in finger joints in healthy controls and early hand osteoarthritis patients using high-resolution MRI
| Autor: | J.W. van Neck, J.M.W. (Mieke) Hazes, Ruud W. Selles, Jolanda J. Luime, M.S. Saltzherr, Galied S. R. Muradin, Ida K. Haugen, J.H. Coert |
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| Přispěvatelé: | Radiology & Nuclear Medicine, Rehabilitation Medicine, Plastic and Reconstructive Surgery and Hand Surgery, Rheumatology, Health Technology Assessment (HTA) |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Adult Cartilage Articular medicine.medical_specialty Adolescent Biomedical Engineering High resolution Proximal interphalangeal joint Metacarpophalangeal Joint 03 medical and health sciences Young Adult 0302 clinical medicine Magnetic resonance imaging Rheumatology Internal medicine Finger Joint Osteoarthritis Hand osteoarthritis medicine Humans Orthopedics and Sports Medicine Metacarpalphalangeal joint 030203 arthritis & rheumatology medicine.diagnostic_test Cartilage thickness business.industry Cartilage Distance score 030104 developmental biology medicine.anatomical_structure Case-Control Studies Lower prevalence Female business Nuclear medicine Kappa |
| Zdroj: | Osteoarthritis and Cartilage, 27(8), 1148-1151. W.B. Saunders Osteoarthritis and Cartilage, 27(8), 1148. W.B. Saunders Ltd |
| ISSN: | 1522-9653 1063-4584 |
| DOI: | 10.1016/j.joca.2019.05.003 |
| Popis: | Summary Objective To compare direct evaluation of cartilage with high resolution Magnetic resonance imaging (MRI) (hrMRI) to indirect cartilage evaluation using MRI inter-bone distance in hand OA patients and healthy controls. Design 41 hand OA patients and 18 healthy controls underwent hrMRI of the 2 nd and 3 rd metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joints. The images were read by two independent readers using OMERACT hand OA MRI inter-bone distance score (0–3 scale) and a new hrMRI cartilage score with direct evaluation of the cartilage (0–3 scale). Inter-reader and intra-reader reliability was calculated using exact and close agreement and kappa values. The prevalence of abnormal scores and agreement between methods was assessed in both hand OA patients and healthy controls. Results The intra- and inter-reader reliability of both scores was comparable, with exact agreement in 73–83% and close agreement in 95–100%. In hand OA patients 27% of 161 joints had both cartilage damage and loss of inter-bone distance, cartilage damage by hrMRI only was present in 20% of joints and reduced inter-bone distance only in 4% of joints. In the healthy controls, 1 of 71 joints were scored as abnormal by both hrMRI and inter bone distance scoring, 1 joint was scored as abnormal using the hrMRI cartilage score only, whereas 15% of joints had only reduced inter bone distance. Conclusions Direct cartilage evaluation of MCP and PIP joints using hrMRI has a good reliability, and the higher prevalence of hrMRI cartilage damage in hand OA patients and the lower prevalence in healthy controls in comparison to evaluation of inter-bone distance suggests a better validity. |
| Databáze: | OpenAIRE |
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